---

"It remains a mystery how the undirected process of mutation, combined
with natural selection, has resulted in the creation of thousands of
new proteins with extraordinarily diverse and well optimized
functions. This problem is particularly acute for tightly integrated
molecular systems that consist of many interacting parts.”

--Two leading biologists in Annual Review of Genomics and Human
Genetics

---

Jahnu wrote:
> [..]

Citatet kommer fra Thornton and DeSalle, Genomics meets phylogenetics,
Annual Review of Genomics and Human Genetics 2000, p. 64.

Se http://arjournals.annualreviews.org/doi/abs/10.1146/annurev.genom.1.1.41

Artiklen handler om (fra abstract)

We also show how the phylogenetic approach makes possible novel kinds of
comparative analysis, including detection of domain shuffling and lateral
gene transfer, reconstruction of the evolutionary diversification of gene
families, tracing of evolutionary change in protein function at the amino
acid level, and prediction of structure-function relationships. A marriage
of the principles of phylogenetic systematics with the copious data
generated by genomics promises unprecedented insights into the nature of
biological organization and the historical processes that created it.

Altså hvordan moderne genetiske metoder vil give ophav til nye dybere
indsigter hvordan biologisk organisation har udviklet sig historiske
(evolutionært).

De to "rigtige videnskabsmænd" kan vi vel alle være helt enige med. ;*)

--
Mvh. Carsten Svaneborg
http://gauss.ffii.org softwarepatent database